- The physical and chemical processes that may affect the ozone layer;
- The human health and other biological effects deriving from any modifications of the ozone layer, particularly those resulting from changes in ultra-violet solar radiation having biological effects (UV-B);
- Climatic effects deriving from any modifications of the ozone layer;
- Effects deriving from any modifications of the ozone layer and any consequent change in UV-B radiation on natural and synthetic materials useful to mankind;
- Substances, practices, processes and activities that may affect the ozone layer, and their cumulative effects;
- Alternative substances and technologies;
- Related socio-economic matters;
and as further elaborated in annexes I and II.
